Pathophysiology

This course is the first of the foundational “3P” (pathophysiology, pharmacology, and physical assessment) courses for advanced nursing practice. It is a fast-paced and in-depth course. The classwork will require time, effort and focus. Viewing content-specific playlists in Osmosis, individual study, exams, and discussion participation are required.
Course Description
The focus of this course for advanced practice nursing students is to apply concepts of pathophysiology from the cellular level to disease process for assessment of patients with a variety of conditions across clinical settings. The concepts and principles of normal physiology, pathophysiology, and genetics are emphasized. Current research is used to explore disruptions in normal physiological functioning. The impact of positive health behaviors on pathophysiology is addressed. A systems approach and psychophysiological interrelationships are used to analyze the disease processes and their causative factors. The course stresses critical thinking and decision-making in clinical settings based on these concepts.

Course Learning Outcomes

1. Explain the primary altered physiology of selected diseases and disorders across the lifespan. (PLO )
2. Explain the secondary effects of altered physiology of selected diseases and disorders on the client. (PLO )
3. Apply the principles of pathophysiology to clients in clinical situations. (PLO )
4. Synthesize and apply rationale for nursing interventions based upon principles of pathophysiology. (PLO )
5. Use pathophysiological knowledge to assess the significance of presenting signs, symptoms, and diagnostic test data. (PLO )
6. Synthesize and apply current evidence based knowledge from research regarding pathophysiology in disease states. (PLO )

ASSIGNMENT
Discussion Prompt
Discuss the differential diagnosis (DD) process. Identify 3 different DD processes used in clinical practice. Describe the risks/benefits of these 3 processes.
Responses to peers should include examples from your clinical setting and case studies from the literature to contribute to the discussion.
It is crucial to appropriately utilize APA 7th ed. All assignments; group work discussions and responses require accurate and appropriate APA citations. It is recommended to use nursing literature, medical literature and ancillary research in other disciplines as necessary. Current citations are required.

When possible evidence-based literature and primary sources that are up to date and are most desirable. Works such as WebMD and the patient “self-help” resources are not appropriate for graduate discussions.

Required STUDY Materials
Rogers, J.L. (2023). McCance & Huether’s Pathophysiology The Biologic Bais for Disease in Adults and Children. Elsevier, St. Louis MO. isbn978-0-323-78987-5
• Unit I: The Cell

• Pages 1-34
• Pages 43-50
• Pages 85-91
• Unit II: Genetics

• Pages 140-162
• Pages 430-439