Prostate Cancer

You will have the opportunity to describe the pathophysiology and pharmacological management for a person suffering from prostate cancer. We would like you to show your understanding by making explicit the links between pathophysiology, clinical manifestations, and pharmacological management of your person’s disease. When preparing your presentation, assume that your target audience is health professionals (e.g., nurses, paramedics, midwives; all of which should have roughly the same base knowledge). Your answers to the questions below will be used to grade the ‘depth’, ‘accuracy’, and ‘clarity’ sections of your Vodcast assignment (see marking rubric provided at the end of this document). At the beginning of your Vodcast, you need to set the scene within the first minute — i.e., tell us about your person, and then proceed to answer the following questions.

You must answer all 3 questions below:

Question 1 Answer both parts (a) and (b).
(a) Discuss the key differences between benign prostate hyperplasia and prostate cancer.
(b) Describe the role of hormones in prostate cancer formation and progression, and discuss strategies that allow differentiation between benign prostate cancer and prostate cancer.

Question 2. Answer both parts (a) and (b).
(a) Describe how mutations in either a proto-oncogene or tumor suppressor gene contribute to the initiation of prostate cancer.
(b) Discuss how metastases can occur in prostate cancer and describe the most common locations where this type of metastatic tumor implants.

Question 3.
Describe the currently available strategies and treatment methods to treat/manage prostate cancer and explain the mechanism of action of at least one of those treatment methods.